What Randomized Controlled Trial means

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What does Randomized Controlled Trial mean?

If you are searching for what Randomized-Controlled Trial means; you are either inquisitive about medical terms, interested in practicing medicine or an aspiring student in the medical field. Whatever the reason may be, Medical Word Meanings (MWM) provides answers to Randomized, Controlled Trial definitions, explanations, and examples.

Randomized Controlled Trial Definitions

American Journal of Roentgenology says Randomized Controlled Trials are used to examine the effect of interventions on particular outcomes such as death or the recurrence of disease. Some consider randomized controlled trials to be the best of all research designs, or “the most powerful tool in modern clinical research”, mainly because the act of randomizing patients to receive or not receive the intervention ensures that, on average, all other possible causes are equal between the two groups. (Source)

Information on Wikipedia states that a randomized controlled trial (RCT) is a type of scientific (often medical) experiment, where the people being studied are randomly allocated one or other of the different treatments under study. RCT is said to be the gold standard for a clinical trial, and are often used to test the efficacy or effectiveness of various types of medical intervention and may provide information about adverse effects, such as drug reactions. (Source)

Randomized Controlled Trial, Explained

Randomized Controlled Trial is simply the study of two treatments in which patients are randomly assigned to get one treatment or the other. This method of trial ensures that the main difference between the two groups of patients is what treatment they got, allowing researchers to compare the benefits and risks of the two approaches. In drug trials, often one of the treatments is an experimental medicine, and the other is a placebo. For most drug approvals, the Food and Drug Administration requires two successful randomized trials.

Randomized Controlled Trial, Examples

For example, imagine that a school seeks to test whether introducing a healthy meal at lunchtime improves the overall fitness of the children. It decides to do this by giving half of the children healthy salads and wholesome meals, whilst the control group carries on as before. At regular intervals, the researchers note the cardiovascular fitness of the children, looking to see if it improves. (Source)

In conclusion, a randomized controlled trial is one of the simplest but most powerful tools of research. In essence, the randomized controlled trial is a study in which people are allocated at random to receive one of several clinical interventions.

The acronym for Randomized Controlled Trial is “RCT“.

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